A “vicious cycle” of NK-cell immune evasion in acute myeloid leukemia mediated by RANKL?

@inproceedings{Schmiedel2013AC,
  title={A “vicious cycle” of NK-cell immune evasion in acute myeloid leukemia mediated by RANKL?},
  author={Benjamin J Schmiedel and Ludger Grosse-Hovest and Helmut Rainer Salih},
  booktitle={Oncoimmunology},
  year={2013}
}
Receptor activator of NFκB ligand (RANKL) is mainly known for its role in bone metabolism, constituting a target for therapeutic interventions. Increasing evidence suggests that RANKL is also involved in oncogenesis and tumor progression, including a prominent role in host-tumor interaction. Our data suggest that targeting RANKL may reinforce natural killer… CONTINUE READING