A (G->C) transversion in the 3' UTR of the human ECP (eosinophil cationic protein) gene correlates to the cellular content of ECP.

@article{Jnsson2006AT,
  title={A (G->C) transversion in the 3' UTR of the human ECP (eosinophil cationic protein) gene correlates to the cellular content of ECP.},
  author={Ulf Lennart Percy J{\"o}nsson and Jonas Bystr{\"o}m and Gunnemar St{\aa}lenheim and Per Venge},
  journal={Journal of leukocyte biology},
  year={2006},
  volume={79 4},
  pages={
          846-51
        }
}
Eosinophil cationic protein (ECP) is a cytotoxic protein produced by and secreted from human eosinophil granulocytes. ECP may be involved in the injury of epithelial cells in allergic diseases such as asthma. The objectives were to determine the prevalence of the ECP gene polymorphism 562(G > C) in apparently healthy subjects and subjects with allergy and relate the prevalence to clinical disease and to serum and cellular levels of ECP. The 562(G > C) ECP gene polymorphism was determined by… CONTINUE READING

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