A "miniacrosome" sperm defect causing infertility in two brothers.

@article{Baccetti1991AS,
  title={A "miniacrosome" sperm defect causing infertility in two brothers.},
  author={Baccio M Baccetti and A G Burrini and Giulia Collodel and Paola Piomboni and Tommaso Renieri},
  journal={Journal of andrology},
  year={1991},
  volume={12 2},
  pages={104-11}
}
A sperm defect causing infertility in two brothers is described. The malformation, named the "miniacrosome sperm defect," occurs in the total sperm population. It involves both the nuclei, which have a roundish apex, and the acrosomes, which are small, located in an apical position on the top of the nucleus, and sometimes ring-shaped. The midpiece and tail segments are normal, and the sperm are perfectly motile but fail to fertilize zona-free hamster ova in vitro. In spermatids, the absence of… CONTINUE READING