99mTc-Labeled UBI 29-41 peptide for monitoring the efficacy of antibacterial agents in mice infected with Staphylococcus aureus.

@article{Nibbering200499mTcLabeledU2,
  title={99mTc-Labeled UBI 29-41 peptide for monitoring the efficacy of antibacterial agents in mice infected with Staphylococcus aureus.},
  author={Peter H Nibbering and Mick M. Welling and Akke Paulusma-Annema and Carlo P J M Brouwer and Antonella Lupetti and Ernest K. J. Pauwels},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2004},
  volume={45 2},
  pages={321-6}
}
UNLABELLED Based on our earlier observation that (99m)Tc-UBI 29-41, a radiolabeled peptide derived from ubiquicidin (UBI), discriminates between infections and sterile inflammatory processes, we considered the possibility that this tracer could be used for monitoring the efficacy of antibacterial agents in animals infected with Staphylococcus aureus. METHODS We injected (99m)Tc-UBI 29-41 into S. aureus-infected mice after treatment with various doses of cloxacillin or erythromycin. At… CONTINUE READING

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99mTc-labeled antimicrobial peptides for detection of bacterial and Candida albicans infections.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine • 2002
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Monitoring the efficacy of antibacterial treatments of infections with 99mTc-labeled antimicrobial peptides [abstract

PH Nibbering, MM Welling, A Paulusma-Annema, MT van den Barselaar, EKJ. Pauwels
Nucl Med Commun • 2000
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