9-Fluoreneacetyl-tagged, solid-phase reagent for derivatization in direct plasma injection.
@article{Zhou19929FluoreneacetyltaggedSR, title={9-Fluoreneacetyl-tagged, solid-phase reagent for derivatization in direct plasma injection.}, author={F. Zhou and I. Krull and B. Feibush}, journal={Journal of chromatography}, year={1992}, volume={609 1-2}, pages={ 103-12 } }
We describe here a resin-based derivatization reagent, containing a 9-fluoreneacetyl tag on a controlled-pore substrate, for direct injection analysis of amphetamine in plasma. On-line, pre-column derivatization was performed by direction injection of diluted plasma sample into an sodium dodecyl sulfate-containing mobile phase. Amphetamine was trapped in the hydrophobic derivatization column and derivatized at elevated temperature by the activated solid-phase reagent. The derivatized 9… CONTINUE READING
Topics from this paper
25 Citations
Derivatization of amines in solid-phase extraction supports with 9-fluorenylmethyl chloroformate for liquid chromatography
- Chemistry
- 1997
- 26
Automated HPLC analyses of drugs of abuse via direct injection of biological fluids followed by simultaneous solid-phase extraction and derivatization with fluorescence detection.
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 1994
- 20
Solid-phase derivatization reactions for biomedical liquid chromatography.
- Chemistry, Medicine
- Journal of chromatography. B, Biomedical applications
- 1994
- 17
Direct determination of adamantanamine in plasma and urine with automated solid phase derivatization.
- Chemistry, Medicine
- Journal of chromatography
- 1993
- 28
Determination of amphetamine and related compounds in urine using on-line derivatization in octadecyl silica columns with 9-fluorenylmethyl chloroformate and liquid chromatography.
- Chemistry, Medicine
- Journal of chromatography. B, Biomedical applications
- 1996
- 23
Automated determination of amphetamine enantiomers using a two-dimensional column-switching chromatographic system for derivatization and separation
- Chemistry
- 1998
- 24
- PDF
Automated pre-column derivatization of amines in biological samples with dansyl chloride and with or without post-column chemiluminescence formation by using TCPO-H2O2.
- Chemistry, Medicine
- The Analyst
- 1998
- 18
- PDF
Polymeric reagents for derivatizations in micellar electrokinetic chromatography.
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 1994
- 4
Amphetamine and methamphetamine determination in urine by reversed-phase high-performance liquid chromatography with simultaneous sample clean-up and derivatization with 1,2-naphthoquinone 4-sulphonate on solid-phase cartridges.
- Chemistry, Medicine
- Journal of chromatography. B, Biomedical applications
- 1996
- 29
Polymeric 6-aminoquinoline, an activated carbamate reagent for derivatization of amines and amino acids by high-performance liquid chromatography.
- Chemistry, Medicine
- Journal of chromatography. B, Biomedical applications
- 1994
- 15
References
SHOWING 1-10 OF 10 REFERENCES
Solid-phase reagent containing the 3,5-dinitrophenyl tag for the improved derivatization of chiral and achiral amines, amino alcohols and amino acids in high-performance liquid chromatography with ultraviolet detection.
- Chemistry, Medicine
- Journal of chromatography
- 1991
- 54
Polymeric activated ester reagents for off-line and on-line derivatizations of amine nucleophiles in high-performance liquid chromatography with ultraviolet and fluorescence detection.
- Chemistry, Medicine
- Analytical chemistry
- 1989
- 36
Determination of enantiomeric drugs in physiological fluids using on-line solid phase derivatizations and reversed-phase liquid chromatography.
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 1989
- 31
Beta-cyclodextrin bonded silica for direct injection analysis of drug enantiomers in serum by liquid chromatography.
- Chemistry, Medicine
- Analytical chemistry
- 1990
- 59
Determination of methotrexate in untreated body fluids by micellar liquid chromatography.
- Chemistry, Medicine
- Analytical chemistry
- 1989
- 39
Analysis of drugs in the presence of serum albumin by liquid chromatography with eluents containing surfactants.
- Chemistry, Medicine
- Analytical chemistry
- 1991
- 21
Characterization of internal surface reversed-phase silica supports for liquid chromatography.
- Chemistry, Medicine
- Journal of chromatography
- 1986
- 256
Direct serum injection with micellar liquid chromatography for therapeutic drug monitoring.
- Chemistry, Medicine
- Analytical chemistry
- 1985
- 123