8q24 amplification in transitional cell carcinoma of bladder.

@article{Visap20038q24AI,
  title={8q24 amplification in transitional cell carcinoma of bladder.},
  author={Harri Visap{\"a}{\"a} and David Seligson and Mervi Eeva and Flora Gaber and J. Thuljaram Rao and Arie S. Belldegrun and Aarno V Palotie},
  journal={Applied immunohistochemistry & molecular morphology : AIMM},
  year={2003},
  volume={11 1},
  pages={33-6}
}
Genomic amplifications of the long arm of chromosome 8q are frequently detected in a number of tumor types, including neoplasias of the urothelium. DNA level amplification and increased expression of at 8q24 is commonly associated with chromosomal gains in this region. Using a urothelial cancer tissue microarray, the authors investigated the 8q24 amplification on bladder tumors and metastases. High-copy 8q24 amplification was detected in 9% (12 of 131) of primary tumors and 33% (6 of 18) of… CONTINUE READING

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The authors conclude that 8q24 amplification occurs in a small subgroup of primary bladder tumors and in a more significant group of distant metastases .
High - copy 8q24 amplification was detected in 9% ( 12 of 131 ) of primary tumors and 33% ( 6 of 18 ) of distant metastases .
The authors conclude that 8q24 amplification occurs in a small subgroup of primary bladder tumors and in a more significant group of distant metastases .
High - copy 8q24 amplification was detected in 9% ( 12 of 131 ) of primary tumors and 33% ( 6 of 18 ) of distant metastases .
The authors conclude that 8q24 amplification occurs in a small subgroup of primary bladder tumors and in a more significant group of distant metastases .
High - copy 8q24 amplification was detected in 9% ( 12 of 131 ) of primary tumors and 33% ( 6 of 18 ) of distant metastases .
The authors conclude that 8q24 amplification occurs in a small subgroup of primary bladder tumors and in a more significant group of distant metastases .
High - copy 8q24 amplification was detected in 9% ( 12 of 131 ) of primary tumors and 33% ( 6 of 18 ) of distant metastases .
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