802 VARIANT VON WILLEBRAND'S DISEASE (vWD): ABNORMALITY IN MULTIMERIC ASSEMBLY OF FACTOR VIII RELATED ANTIGEN (VIIIRAg)

Abstract

Factor VIII in normal plasma is a complex of at least two molecules, VIIIRAg and VIIIC, each having distinct functional and antigenic properties. VIIIRAg normally assembles as a series of multimeric forms ranging from 1 to >20×106 daltons. We show, using a new crossed immuno-electrophoresis procedure, the importance of identifying alterations in the… (More)
DOI: 10.1203/00006450-198104001-00826

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