8-O-demethylchelerythrine fromMacleaya cordata

  title={8-O-demethylchelerythrine fromMacleaya cordata},
  author={O. N. Tolkachev and A. Savina and V. I. Sheichenko and V. V. Proskudina},
  journal={Pharmaceutical Chemistry Journal},
The fractions obtained upon chromatographic separation of the sum of quaternary benzo[c]phenanthridine alkaloids from Macleaya cordata contain, besides sanguinarine (I) and chelerythrine (1I), an admixture of a substance (III) having the form of golden-brownish needle crystals (whiskers), having a melting point of 220-226~ (from chloroform) and losing transparency at 167~ The IH NMR spectrum of compound III is typical of the 2,3,7,8-substituted quaternary benzo[c]phenanthridine alkaloids and is… Expand
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