8-O-cinnamoylneoline, a new alkaloid from the flower buds of Aconitum carmichaeli and its toxic and analgesic activities.

@article{Taki20038OcinnamoylneolineAN,
  title={8-O-cinnamoylneoline, a new alkaloid from the flower buds of Aconitum carmichaeli and its toxic and analgesic activities.},
  author={Masanori Taki and Kazuaki Niitu and Yuji Omiya and Masamichi Noguchi and Mikio Fukuchi and Masaki Aburada and Minoru Okada},
  journal={Planta medica},
  year={2003},
  volume={69 9},
  pages={800-3}
}
From flower buds of Aconitum carmichaeli Debx., a new alkaloid, 8- O-cinnamoylneoline, was isolated. The structure of the new alkaloid was determined by spectral analysis, and the alkaloid was examined for its toxic and analgesic activities. Its LD50 value was 11.89 mg/kg (s.c.) in mice: the toxicity was 1/30 times that of mesaconitine and 20 times that of… CONTINUE READING