8-Methoxypsoralen and long-wave ultraviolet A inhibit the release of proinflammatory mediators and cytokines from human Fc epsilon RI+ cells: an in vitro study.

@article{Paulis20038MethoxypsoralenAL,
  title={8-Methoxypsoralen and long-wave ultraviolet A inhibit the release of proinflammatory mediators and cytokines from human Fc epsilon RI+ cells: an in vitro study.},
  author={Amato de Paulis and Giuseppe Monfrecola and Lucia Casula and Emilia Prizio and Luisa Di Gioia and Maria Francesca Carfora and Irene Russo and Gennaro de Crescenzo and Gianni Marone},
  journal={Journal of photochemistry and photobiology. B, Biology},
  year={2003},
  volume={69 3},
  pages={169-77}
}
The in vitro effects of 8-MOP (concentrations of 20, 100 and 500 ng/ml) alone or in combination with UVA on mediator release from human basophils and skin mast cells (HSMC), activated with immunological and non-immunological stimuli, were investigated. With respect to basophils activated with anti-IgE serum, the results of this study show that: (i) 8-MOP… CONTINUE READING