8;21 translocation in acute granulocytic leukaemia: cytological, cytochemical and clinical features.

@article{Swirsky1984821TI,
  title={8;21 translocation in acute granulocytic leukaemia: cytological, cytochemical and clinical features.},
  author={David Michael Swirsky and You. S. Li and John Graham Matthews and R. J. Flemans and John K. H. Rees and F. J. G. Hayhoe},
  journal={British journal of haematology},
  year={1984},
  volume={56 2},
  pages={199-213}
}
Thirty patients with the 8;21 translocation and three with closely related variants have been studied. Ages ranged from 3 to 64 years (mean 28.3). Thirty-one were entered into the MRC's 8th Acute Myeloid Leukaemia Trial. Twenty-nine (88%) achieved complete remission. Marrow smears from most patients showed granulocytic maturation (M2, FAB classification) with characteristic abnormalities, but at least six showed predominantly myeloblastic (M1) morphology. The blast cells were markedly… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 47 extracted citations

Diagnostic complexities of eosinophilia.

Archives of pathology & laboratory medicine • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…