7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells

Abstract

Development of more effective therapeutic strategies for cancers of high unmet need requires the continued discovery of disease-specific protein targets for therapeutic antibody targeting. In order to identify novel proteins associated with cancer cell invasion/metastasis, we present here an alternative to antibody targeting of cell surface proteins with an… (More)
DOI: 10.1007/s13277-014-1857-5

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Cite this paper

@article{OSullivan20147B7AN, title={7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells}, author={Dermot M. O’Sullivan and Michael Henry and Helena Joyce and Naomi Walsh and Edel Mc Auley and Paul A Dowling and Niall C. Swan and Michael J Moriarty and Paul Barnham and Martin M. Clynes and Annemarie Larkin}, journal={Tumor Biology}, year={2014}, volume={35}, pages={6983-6997} }