767 Type 14 Pneumococcal Antisera Is Opsonic in Vitro and Protective in Vivo for Group B Streptococcus Type Iii

@article{Fischer1978767T1,
  title={767 Type 14 Pneumococcal Antisera Is Opsonic in Vitro and Protective in Vivo for Group B Streptococcus Type Iii},
  author={Gerald W. Fischer and George H. Lowell and Martin H Crumrine and James W Bass},
  journal={Pediatric Research},
  year={1978},
  volume={12},
  pages={491-491}
}
The absence of type specific opsonic antibody in maternal and cord sera has been shown to be a major determinant for the development of invasive neonatal group B streptococcal (GBS) disease. Using immunoelectrophoresis we recently showed that antibody to Streptococcus pneumonia type 14 (SP14) reacted with the hot HC1 extracted polysaccharide antigen of GBS type III (GBS III). The present studies were designed to determine if SP14 antibody is opsonic for GBS III in vitro and protective in vivo… CONTINUE READING