7-Deazapurine biosynthesis: NMR study of toyocamycin biosynthesis in Streptomyces rimosus using 2-13C-7-15N-adenine.

Abstract

Although 7-deazapurines are well known and feature in the hypermodified RNA base queuosine, and in a range of nucleoside antibiotics such as toyocamycin, a mechanistic understanding of their biosynthesis is a longstanding problem. In particular, the obligatory loss of the N-7 nitrogen atom is puzzling, and in order to address this mechanistic conundrum a… (More)
DOI: 10.1039/c0ob01054e

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Cite this paper

@article{Battaglia20117DeazapurineBN, title={7-Deazapurine biosynthesis: NMR study of toyocamycin biosynthesis in Streptomyces rimosus using 2-13C-7-15N-adenine.}, author={Ugo Battaglia and Jed E. Long and M. S. Searle and Christopher J Moody}, journal={Organic & biomolecular chemistry}, year={2011}, volume={9 7}, pages={2227-32} }