7-Deazapurine (Pyrrolo[2,3-d]pyrimidine) 2-Deoxyribonucleosides: Syntheses and Transformations

@article{Seela20127Deazapurine2,
  title={7-Deazapurine (Pyrrolo[2,3-d]pyrimidine) 2-Deoxyribonucleosides: Syntheses and Transformations},
  author={F. Seela and S. Budow and Xiaohua Peng},
  journal={Current Organic Chemistry},
  year={2012},
  volume={16},
  pages={161-223}
}
Abstract: This review reports on the synthesis of 7-deazapurine (pyrrolo[2,3-d]pyrimidine) 2’-deoxyribonucleosides, including -Dand -L-enantiomers, fluoro derivatives, and 2’,3’-dideoxyribonucleosides. It covers the various aspects of convergent nucleoside synthesis. Stereochemically defined -D and -L 2’-deoxyribonucleosides as well as sugar derivatives were prepared by nucleobase anion glycosylation. This glycosylation reaction is regioselective for the pyrrole nitrogen and stereoselective for… Expand
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