7,12-dimethylbenz[a] anthracene--DNA binding in mouse skin: response of different mouse strains and effects of various modifiers of carcinogenesis.

Abstract

7,12-Dimethylbenz[a]anthracene (DMBA)--deoxyribonucleoside adducts formed in mouse skin DNA were quantified in order to determine whether these changed in any systematic fashion under conditions where the tumorigenic activity of DMBA is modified. Similar distributions of adducts were found in male NIH Swiss mice and C57BL mice which exhibit different… (More)

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