6-hydroxydopamine and the blood-brain barrier in adult conscious rats.

Abstract

6-hydroxydopamine (6-OHDA), 15 or 50 mg . kg-1 given as bolus i.v. injection to adult conscious rats with aortic catheter, rapidly increased mean arterial pressure by 70-78 mmHg. The pressure returned to normal within 40-60 min. The cerebrovascular permeability in rats given 6-OHDA and sacrificed 10 or 60 min later was enhanced as indicated by extravasation… (More)

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@article{Johansson19806hydroxydopamineAT, title={6-hydroxydopamine and the blood-brain barrier in adult conscious rats.}, author={B{\"o}rje Johansson and M. Henning}, journal={Acta physiologica Scandinavica}, year={1980}, volume={110 1}, pages={1-4} }