6% Hydroxyethyl starch (130/0.4) vs Ringer's lactate preloading before spinal anaesthesia for Caesarean delivery: the randomized, double-blind, multicentre CAESAR trial.

@article{Mercier20146HS,
  title={6% Hydroxyethyl starch (130/0.4) vs Ringer's lactate preloading before spinal anaesthesia for Caesarean delivery: the randomized, double-blind, multicentre CAESAR trial.},
  author={Fr{\'e}d{\'e}ric Jean Mercier and Pierre A. Diemunsch and Anne-Sophie Ducloy-Bouthors and Alexandre Mignon and Marc Fischler and J M Malinovsky and Franck Bolandard and Antoine G. M. Aya and Marc Raucoules-Aim{\'e} and Dominique Chassard and Hawa Keita and Agn{\`e}s Rigouzzo and Agn{\`e}s Le Gouez},
  journal={British journal of anaesthesia},
  year={2014},
  volume={113 3},
  pages={459-67}
}
BACKGROUND Vasopressor administration is recommended to prevent hypotension during spinal anaesthesia (SA) for elective Caesarean delivery. We aimed to test the superior efficacy and ensure safety of a hydroxyethyl starch (HES) vs a Ringer's lactate (RL) preloading, when combined with a phenylephrine-based prophylaxis. METHODS A total of 167 healthy parturients undergoing elective Caesarean delivery under SA were included in this multicentre, randomized, double-blind study. Patients received… CONTINUE READING
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