5HTT genotype moderates the influence of early institutional deprivation on emotional problems in adolescence: evidence from the English and Romanian Adoptee (ERA) study.

@article{Kumsta20105HTTGM,
  title={5HTT genotype moderates the influence of early institutional deprivation on emotional problems in adolescence: evidence from the English and Romanian Adoptee (ERA) study.},
  author={Robert Kumsta and Suzanne E Stevens and Keeley J. Brookes and Wolff Schlotz and Jenny Castle and Christopher Beckett and Jana M. Kreppner and Michael D. Rutter and Edmund Sonuga-Barke},
  journal={Journal of child psychology and psychiatry, and allied disciplines},
  year={2010},
  volume={51 7},
  pages={
          755-62
        }
}
BACKGROUND A common polymorphism in the serotonin transporter gene (SLC6A4, 5HTT) has been repeatedly shown to moderate the influence of childhood adversity and stressful life events on the development of psychopathology. Using data from the English and Romanian Adoptee Study, a prospective-longitudinal study of individuals (n = 125) exposed to severe early institutional deprivation (ID), we tested whether the effect of ID on adolescent emotional problems is moderated by 5HTT genotype and… CONTINUE READING
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