53BP1, an activator of ATM in response to DNA damage.


p53 Binding protein 1 (53BP1) belongs to a family of evolutionarily conserved DNA damage checkpoint proteins with C-terminal BRCT domains and is most likely the human ortholog of the budding yeast Rad9 protein, the first cell cycle checkpoint protein to be described. 53BP1 localizes rapidly to sites of DNA double strand breaks (DSBs) and its initial… (More)


Cite this paper

@article{Mochan200453BP1AA, title={53BP1, an activator of ATM in response to DNA damage.}, author={Tamara A. Mochan and Monica Venere and Richard A Ditullio and Thanos D Halazonetis}, journal={DNA repair}, year={2004}, volume={3 8-9}, pages={945-52} }