50th anniversary of the discovery of ibuprofen: an interview with Dr Stewart Adams

  title={50th anniversary of the discovery of ibuprofen: an interview with Dr Stewart Adams},
  author={Gayle M Halford and M. Lordkipanidz{\'e} and S. Watson},
  pages={415 - 422}
  • Gayle M Halford, M. Lordkipanidzé, S. Watson
  • Published 2012
  • Medicine
  • Platelets
  • 2011 marks the 50th anniversary of the discovery of ibuprofen. This article is a focus on the personal reflections and career of Dr Stewart Adams OBE, the scientist whose research lead to the discovery of the cyclooxygenase inhibitor. When Dr Adams discovered ibuprofen, he was working as a pharmacologist in the Research Department for the Boots Pure Drug Company Ltd. Dr Adams was assigned to work on rheumatoid arthritis (RA) and chose in 1953 to search for a drug that would be effective in RA… CONTINUE READING
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    The Propionic Acids: A Personal Perspective
    • S. S. Adams
    • Medicine
    • Journal of clinical pharmacology
    • 1992
    • 60
    • Highly Influential
    Ibuprofen: pharmacology, efficacy and safety
    • 266
    Ibuprofen, the propionics and NSAIDs: Personal reflections over four decades
    • S. Adams
    • Medicine
    • InflammoPharmacology
    • 1999
    • 15
    • Highly Influential
    Ibuprofen: a journey from prescription to over-the-counter use.
    • N. Moore
    • Medicine
    • Journal of the Royal Society of Medicine
    • 2007
    • 28
    • Highly Influential
    Penicillin: its discovery and early development.
    • B. L. Ligon
    • Medicine
    • Seminars in pediatric infectious diseases
    • 2004
    • 131
    The effect of ibuprofen on platelet function in vivo.
    • Y. Ikeda
    • Medicine
    • The Keio journal of medicine
    • 1977
    • 21
    Absorption, distribution and toxicity of ibuprofen.
    • 149
    The metabolism of ibuprofen.
    • 203
    Use of ibuprofen and risk of Parkinson disease
    • 225
    Effect of ibuprofen on platelet function in normal subjects and hemophiliac patients
    • 59