500,000 fish phenotypes: The new informatics landscape for evolutionary and developmental biology of the vertebrate skeleton

@inproceedings{Mabee2012500000FP,
  title={500,000 fish phenotypes: The new informatics landscape for evolutionary and developmental biology of the vertebrate skeleton},
  author={Paula M. Mabee and James P. Balhoff and Wasila M. Dahdul and Hilmar Lapp and Peter E. Midford and Todd J. Vision and Monte Westerfield},
  booktitle={Zeitschrift fur angewandte Ichthyologie = Journal of applied ichthyology},
  year={2012}
}
The rich phenotypic diversity that characterizes the vertebrate skeleton results from evolutionary changes in regulation of genes that drive development. Although relatively little is known about the genes that underlie the skeletal variation among fish species, significant knowledge of genetics and development is available for zebrafish. Because developmental processes are highly conserved, this knowledge can be leveraged for understanding the evolution of skeletal diversity. We developed the… CONTINUE READING
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