5-year clinical outcomes after sirolimus-eluting stent implantation insights from a patient-level pooled analysis of 4 randomized trials comparing sirolimus-eluting stents with bare-metal stents.

@article{Caixeta20095yearCO,
  title={5-year clinical outcomes after sirolimus-eluting stent implantation insights from a patient-level pooled analysis of 4 randomized trials comparing sirolimus-eluting stents with bare-metal stents.},
  author={Adriano Mendes Caixeta and Martin B. Leon and Alexandra J Lansky and Eugenia Nikolsky and Jiro Aoki and Jeffrey W. Moses and Joachim J Schofer and Marie-claude Morice and Erick Schampaert and Ajay J. Kirtane and Jeffrey J. Popma and Helen Parise and Martin Fahy and Roxana Mehran},
  journal={Journal of the American College of Cardiology},
  year={2009},
  volume={54 10},
  pages={894-902}
}
OBJECTIVES Five-year clinical follow-up has been scheduled per protocol by the 4 Cypher (Cordis/Johnson & Johnson, Warren, New Jersey) sirolimus-eluting stent (SES) versus bare-metal stent (BMS) randomized trials. BACKGROUND A delayed arterial healing response after drug-eluting stent implantation has raised concerns about the long-term safety of drug-eluting stents. METHODS In a pooled analysis of 4 randomized trials, 1,748 patients were assigned to receive either an SES (n = 878) or BMS… CONTINUE READING

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