5-methylcytosine-selective osmium oxidation.

Abstract

Methylcytosine was efficiently and easily modified through osmium oxidation. Methylcytosine-selective oxidation is applicable to detection of the cytosine methylation status at a specific site of a long sequence using the formation of a bulge structure by hybridization with a guide DNA. 

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Cite this paper

@article{Okamoto20075methylcytosineselectiveOO, title={5-methylcytosine-selective osmium oxidation.}, author={Akimitsu Okamoto}, journal={Nucleosides, nucleotides & nucleic acids}, year={2007}, volume={26 10-12}, pages={1601-4} }