5-hydroxytryptophan Decarboxylase in Rat Brain: Effect of Hypothalamic Lesions.


Section of the medial forebrain bundle within the lateral hypothalamus of the rat reduces the serotonin content and the 5-hydroxytryptophan decarboxylase activity in the brain. The integrity of this fiber tract appears necessary for the maintenance of normal concentrations of the amine and enzyme in the telencephalon. 


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