5-ht1a Receptor Imaging in the Human Brain: Effect of Tryptophan Depletion and Infusion on [f]-mppf Binding

Abstract

The 5-HT 1A receptor has been implicated in a variety of physiological processes, psychiatric disorders and neurodegenerative disorders. [ 18 F]-MPPF is a useful radioligand for quantitative imaging of 5-HT 1A receptors in human subjects. Previous studies have shown that the binding of some radioligands is sensitive to changes in neurotransmitter… (More)

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@inproceedings{Haes20055ht1aRI, title={5-ht1a Receptor Imaging in the Human Brain: Effect of Tryptophan Depletion and Infusion on [f]-mppf Binding}, author={Joanna I. Udo de Haes and Fokko J. Bosker and Aren van Waarde and Jan Pruim and Antoon T. M. Willemsen and Willem Vaalburg and J. A. den Boer}, year={2005} }