5-fluorouracil increases the number and complexity of premature complexes in the heart: a prospective study using ambulatory ECG monitoring.

@article{Yilmaz20075fluorouracilIT,
  title={5-fluorouracil increases the number and complexity of premature complexes in the heart: a prospective study using ambulatory ECG monitoring.},
  author={Ugur Cem Yilmaz and Ilhan Oztop and Arif Çiloğlu and Taha Okan and Uğur Tekin and Arzu Yaren and Isil Somali and Ahmet Alacacioğlu and Onder Kirimli},
  journal={International journal of clinical practice},
  year={2007},
  volume={61 5},
  pages={795-801}
}
The cardiac toxicity of LV5FU2 (de Gramont) regimen which is a widely used chemotherapy regimen in gastrointestinal system cancers is not well defined. We aimed to evaluate the impact of this regimen on cardiac rhythm. Two Holter ECG recordings were obtained in all patients with gastrointestinal system cancers treated with LV5FU2 regimen as first-line chemotherapy (one before and the second during the first 24 h of chemotherapy). Records were reviewed for the heart rate, rhythm, atrial… CONTINUE READING

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