5-fluoro-D,L-tryptophan as a dual NMR and fluorescent probe of α-synuclein.


Analysis of conventional proton nuclear magnetic resonance (NMR) experiments on intrinsically disordered proteins (IDPs) is challenging because of the highly flexible and multiple rapidly exchanging conformations typifying this class of proteins. One method to circumvent some of these difficulties is to incorporate nonnative fluorine ((19)F) nuclei at… (More)
DOI: 10.1007/978-1-61779-927-3_14


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