Corpus ID: 24206591

5-OH-dopa, product of and substrate for tyrosinase.

@article{Agrup19825OHdopaPO,
  title={5-OH-dopa, product of and substrate for tyrosinase.},
  author={Gun Agrup and Hans Rorsman and Evald Rosengren},
  journal={Acta dermato-venereologica},
  year={1982},
  volume={62 5},
  pages={
          371-76
        }
}
The formation of 5-OH-dopa on incubation of tyrosine or dopa with mushroom tyrosinase was studied. Dopa oxidase activity was defined by measuring the formation of 5-S- and 2-S-cysteinyldopa from dopa in the presence of excess amounts of cysteine. This procedure quantitating the immediate nucleophilic reaction products of dopaquinone constitutes a new method for assessing tyrosinase activity. The rate of 5-OH-dopa formation from dopa was similar to that of the formation of dopa from tyrosine… Expand
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