5'-Nucleotides as potential formulations for administering nucleoside analogs in man.

Abstract

A variety of nucleoside analogs have shown carcinostatic activity. In some instances they are relatively rapidly excreted. In others they are relatively rapidly inactivated in vivo by catabolic enzymes. In both cases it appeared desirable to have nucleoside derivatives that would act as depot forms of the nucleoside analogs and would be converted in vivo to… (More)

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Cite this paper

@article{Lepage19725NucleotidesAP, title={5'-Nucleotides as potential formulations for administering nucleoside analogs in man.}, author={G A Lepage and Yin Tzu Lin and Ronald Orth and Jeffery A. Gottlieb}, journal={Cancer research}, year={1972}, volume={32 11}, pages={2441-4} }