5-Methylcytosine localised in mammalian constitutive heterochromatin

  title={5-Methylcytosine localised in mammalian constitutive heterochromatin},
  author={Orlando J. Miller and Wolfgang Schnedl and Julian Allen and Bernard F. Erlanger},
DEOXY-5-METHYLCYTIDYLIC acid (5-MeC) is an almost universal, although minor component of DNA in plants and animals. It makes up 4–7% of the bases in plants1, no more than 1.5% of the bases in the mouse2 and even less in the human3. 5-MeC itself is not incorporated directly into DNA. Instead, specific deoxycytidylic acid residues in preformed DNA are methylated enzymatically by a highly specific DNA methylase, which transfers a methyl group from S-adenosyl methionine to specific sites in DNA4… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 85 extracted citations

Imaging and Tracking Stem Cells

Methods in Molecular Biology • 2013
View 3 Excerpts
Highly Influenced

Regulation of Peripheral Nerve Myelin Maintenance by Gene Repression through Polycomb Repressive Complex 2.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2015
View 1 Excerpt

Third Report on Chicken Genes and Chromosomes 2015.

Cytogenetic and genome research • 2015
View 2 Excerpts

Similar Papers

Loading similar papers…