5 Long-term acromegaly and associated cardiovascular complications: a case-based review.

@article{Colao20095LA,
  title={5 Long-term acromegaly and associated cardiovascular complications: a case-based review.},
  author={Annamaria Colao},
  journal={Best practice & research. Clinical endocrinology & metabolism},
  year={2009},
  volume={23 Suppl 1},
  pages={S31-8}
}
Because growth hormone and IGF-1 both have regulatory roles in the cardiovascular system, patients with acromegaly often present with abnormalities of heart structure and function and the vascular system, which if left unmanaged can reduce life expectancy. Early symptoms of acromegalic cardiomyopathy (hyperkinetic syndrome) can be characterized by cardiac hypertrophy, increased heart rate, and increased systolic output. When left untreated, more pronounced hypertrophy, signs of diastolic… CONTINUE READING