5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects.

  title={5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects.},
  author={William Byerley and Lewis L. Judd and Frederick W Reimherr and Bernard I. Grosser},
  journal={Journal of clinical psychopharmacology},
  volume={7 3},
Alterations in serotonin metabolism may be an important factor in the etiology and treatment of depression. In this regard, 5-hydroxytryptophan (5-HTP), a serotonin precursor, has been given to patients with depression. Although a review of these studies suggests that 5-HTP possesses antidepressant properties, additional trials are clearly indicated. Following a discussion of the pharmacology of 5-HTP, the authors highlight adverse effects associated with its administration to depressed… CONTINUE READING

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