5-Hydroxytryptamine responses in immature rat rostral ventrolateral medulla neurons in vitro.

@article{Hwang19985HydroxytryptamineRI,
  title={5-Hydroxytryptamine responses in immature rat rostral ventrolateral medulla neurons in vitro.},
  author={Lee-juan Hwang and Nae J. Dun},
  journal={Journal of neurophysiology},
  year={1998},
  volume={80 3},
  pages={1033-41}
}
Whole cell patch recordings were made from rostral ventrolateral medullar (RVLM) neurons of brain-stem slices from 8- to 12-day-old rats. By superfusion or pressure ejection to RVLM neurons, 5-hydroxytryptamine (5-HT) elicited three types of membrane potential changes: a slow hyperpolarization (5-HTH), a slow depolarization (5-HTD) and a biphasic response, which persisted in a tetrodotoxin (TTX, 0.3 microM)-containing solution. 5-HTH were accompanied by a decrease of input resistance in the… CONTINUE READING