5-Hydroxytryptamine-induced outward currents mediated via 5-HT(1A) receptors in neurons of the rat dorsolateral septal nucleus.

@article{Yamada20005HydroxytryptamineinducedOC,
  title={5-Hydroxytryptamine-induced outward currents mediated via 5-HT(1A) receptors in neurons of the rat dorsolateral septal nucleus.},
  author={Kiyoyasu Yamada and Hiroshi Hasuo and Chikage Murakami and Yasuyoshi Yasaka and Tsutomu Fujimura and Takashi Akasu},
  journal={Neuroscience research},
  year={2000},
  volume={37 4},
  pages={307-14}
}
Effects of 5-hydroxytryptamine (5-HT) on neurons of the rat dorsolateral septal nucleus (DLSN) were examined by intracellular and whole-cell patch-clamp recording techniques. An outward current was induced by 5-HT (1-100 microM) in a concentration-dependent manner. The EC(50) for 5-HT was 4.8 microM. Also, 8-OH-DPAT (10-100 microM) produced the outward… CONTINUE READING