5-HTTLPR short allele, resilience, and successful aging in older adults.

  title={5-HTTLPR short allele, resilience, and successful aging in older adults.},
  author={Ruth Oʼhara and Peter Marcus and Wesley K. Thompson and John C. Flournoy and Ipsit V. Vahia and Xiaoyan Lin and Joachim F. Hallmayer and Colin A Depp and Dilip V. Jeste},
  journal={The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  volume={20 5},
OBJECTIVE Resilience is proposed as a significant component of successful aging. Young adult carriers of the Serotonin Transporter Polymorphism (5-HTTLPR) short(s) allele appear to have reduced resilience to stress. We examined whether the presence of the short allele was associated with poorer emotional resilience in older adults. METHODS In a cross-sectional study of 99 healthy, community-dwelling, older adults, we determined 5-HTTLPR genotype status and administered the Connor-Davidson… CONTINUE READING