5-HTTLPR genotype, stressful life events and late-life depression: no evidence of interaction in a French population.

@article{Power20105HTTLPRGS,
  title={5-HTTLPR genotype, stressful life events and late-life depression: no evidence of interaction in a French population.},
  author={Tom Power and Robert Stewart and M-L. Ancelin and Isabelle Jaussent and Alain Malafosse and Karen Ritchie},
  journal={Neurobiology of aging},
  year={2010},
  volume={31 5},
  pages={886-7}
}
Modification of the effect of life events on risk of depression by a polymorphism in the serotonin transporter gene promoter (5-HTTLPR) has been reported in child, adolescent, adult and elderly populations. Replication attempted on data collected from 1421 individuals aged 65 and over from a French community study provided no evidence of a similar modifying effect. In the only analysis known to the authors to be carried out in an exclusively elderly, European population, this null finding… CONTINUE READING

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