5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene and irritable bowel syndrome: effect of bowel habit and sex.

@article{Niesler20105HTTLPRAS,
  title={5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene and irritable bowel syndrome: effect of bowel habit and sex.},
  author={B Niesler and Johannes Kapeller and Catherine Fell and Wendy L. Atkinson and Dorothee M{\"o}ller and Christine Fischer and Peter J Whorwell and L A Houghton},
  journal={European journal of gastroenterology & hepatology},
  year={2010},
  volume={22 7},
  pages={856-61}
}
BACKGROUND Conflicting data exist on the association between functional polymorphisms in the serotonin reuptake transporter (SERT) gene (SLC6A4) and irritable bowel syndrome (IBS). This may be partly because of small participant numbers and varying ethnic origin and sex within the cohorts studied. AIM To reassess the potential association between the SERT polymorphisms 5-HTTLPR and STin2 in both male and female IBS patients with diarrhoea (IBS-D) and constipation (IBS-C) compared with healthy… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 33 references

A genetic association study of 5-HTT LPR and GNbeta3 C825T polymorphisms with irritable bowel syndrome.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society • 2007

Sigmoid-colonic motility in health and irritable bowel syndrome: a role for 5-hydroxytryptamine.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society • 2007

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