5-HT2A receptor antagonist increases circulating adiponectin in patients with type 2 diabetes.

@article{Nomura20055HT2ARA,
  title={5-HT2A receptor antagonist increases circulating adiponectin in patients with type 2 diabetes.},
  author={Shosaku Nomura and Akira Shouzu and Seitarou Omoto and Mitsushige Nishikawa and Toshiji Iwasaka},
  journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis},
  year={2005},
  volume={16 6},
  pages={423-8}
}
We compared the levels of plasma adiponectin, platelet activation markers (P-selectin, CD63, PAC-1, annexin V, and platelet-derived microparticles), and endothelial injury markers (soluble E-selectin and soluble vascular cell adhesion molecule-1) in 53 patients with type 2 diabetes mellitus to investigate potential contributions to diabetic vascular complications. In addition, we administered serotonin antagonist (sarpogrelate hydrochloride) to type 2 diabetes patients who had increased soluble… CONTINUE READING

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