5-HT1B receptors, ventral orbitofrontal cortex, and aggressive behavior in mice

Abstract

Systemic injections of 5-HT1B receptor agonists have been shown to have specific anti-aggressive effects in aggressive individuals. One site of action for these drugs is the 5-HT1B receptors in the ventral orbitofrontal cortex (VO PFC), an area that has been implicated in the inhibitory control of behavior and is a terminal region for 5-HT projections. To… (More)
DOI: 10.1007/s00213-006-0333-3

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