5-HT1A receptors direct the orientation of plasticity in layer 5 pyramidal neurons of the mouse prefrontal cortex

@article{Meunier20135HT1ARD,
  title={5-HT1A receptors direct the orientation of plasticity in layer 5 pyramidal neurons of the mouse prefrontal cortex},
  author={Claire N. J. Meunier and Michel Amar and Laurence Lanfumey and Michel Hamon and Philippe Fossier},
  journal={Neuropharmacology},
  year={2013},
  volume={71},
  pages={37-45}
}
Several psychiatric disorders involving the prefrontal cortex (PFC) are associated with a dysfunction of 5-HT(1A) receptors (5-HT(1A)R). These receptors, located on interneurons and pyramidal neurons, may influence neuronal excitability through a regulation of the balance between excitation (E) and inhibition (I). Patch-clamp recordings in mouse cortical slices were performed to determine the modulatory role of 5-HT(1A)R on the excitability and the synaptic plasticity of layer 5 pyramidal… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

Monoaminergic Modulation of Motor Cortex Function

  • Front. Neural Circuits
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 59 REFERENCES

Serotoninergic finetuning of the excitation-inhibition balance in rat visual cortical networks

A. W. Moreau, M. Amar, N. Le Roux, N. Morel, P. Fossier
  • Cereb. Cortex
  • 2010
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Deaf-1 knockout mice display increased 5-HT1A autoreceptor expression and reduced raphe serotonin levels

M. Czesak, B. Le François, A. M. Millar, M. Deria, M Daigle
  • J. Biol
  • 2012
VIEW 2 EXCERPTS