5-HT1A receptor activation improves anti-cataleptic effects of levodopa in 6-hydroxydopamine-lesioned rats

Abstract

BACKGROUND AND THE PURPOSE OF THE STUDY In Parkinson›s disease (PD) prolong use of L-DOPA causes some motor disorders such as wearing-off and L-DOPA induced dyskinesia (LID). In this investigation the effect of 8-OHDAPT, as a 5-HT(1A) agonist on anti-cataleptic effect of L-DOPA in 6-hydroxydopamine (6-OHDA) lesioned male Wistar rats was investigated… (More)

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@inproceedings{Mahmoudi20115HT1ARA, title={5-HT1A receptor activation improves anti-cataleptic effects of levodopa in 6-hydroxydopamine-lesioned rats}, author={Javad Mahmoudi and Alireza Mohajjel Nayebi and Morteza Samini and Siyamak Reyhani-Rad and Vahab Babapour}, booktitle={Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences}, year={2011} }