5-HT and alcohol abuse.

  title={5-HT and alcohol abuse.},
  author={Edward M. Sellers and Guy A Higgins and Mark B. Sobell},
  journal={Trends in pharmacological sciences},
  volume={13 2},
Recent experimental data, both in animals and the clinic, suggest that drugs selectively interacting with the 5-HT system may reduce alcohol intake. Although the precise mechanisms underlying these drug effects are unknown, it seems that there are at least two pharmacological strategies available, described in this review by Edward Sellers and colleagues. The first is enhancement of 5-HT neuronal activity using compounds that will release 5-HT, block 5-HT reuptake, or act as selective 5-HT… CONTINUE READING

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