5-Fluorouracil filtering surgery and neovascular glaucoma. Long-term follow-up of the original pilot study.

@article{Tsai19955FluorouracilFS,
  title={5-Fluorouracil filtering surgery and neovascular glaucoma. Long-term follow-up of the original pilot study.},
  author={James C Tsai and William J Feuer and Richard K. Parrish and A L Grajewski},
  journal={Ophthalmology},
  year={1995},
  volume={102 6},
  pages={887-92; discussion 892-3}
}
BACKGROUND The long-term efficacy and safety of filtering surgery with 5-fluorouracil (5-FU) in eyes with neovascular glaucoma are unknown. METHODS Kaplan-Meier survival curve analysis of surgical outcome was performed on all 34 patients (34 eyes) enrolled from May 1982 through April 1986 in the original pilot study of filtering surgery with 5-FU. RESULTS Success rates at the 1-, 2-, 3-, 4-, and 5-year intervals were 71%, 67%, 61%, 41%, and 28%, respectively. The median filter survival time… CONTINUE READING

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