5-ALA fluorescence-guided surgery of CNS tumors

  title={5-ALA fluorescence-guided surgery of CNS tumors},
  author={Constantinos G Hadjipanayis and Walter Stummer and Jason P Sheehan},
  journal={Journal of Neuro-Oncology},
The recent Food and Drug Administration (FDA) approval of 5-ALA (5-aminovelulinic acid; Gleolan®; photonamic GmbH & Co. KG) for use as an intraoperative optical imaging agent in patients with suspected high-grade gliomas (HGGs) in 2017 catapulted fluorescence-guided surgery (FGS) as a new standard for neurosurgeons and their patients in the United States (US) [1]. This would be the first ever optical imaging agent or tool approved for use in neurosurgery in the US. Over 20 years have passed… CONTINUE READING
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