5 α-Reductase Type 2 Deficiency — Response to Dihydrotestosterone Gel: Authors’ Reply

@article{Vupputuri20135T,
  title={5 $\alpha$-Reductase Type 2 Deficiency — Response to Dihydrotestosterone Gel: Authors’ Reply},
  author={Madhava Rao Vupputuri and Madhurima Kandepu and Harikishore Reddy Devireddy},
  journal={The Indian Journal of Pediatrics},
  year={2013},
  volume={81},
  pages={985}
}
To the Editor: We read with great interest the letter by Ammini et al. on our article “5 α-reductase type 2 deficiency—Response to dihydrotestosterone gel” [1]. While Ammini et al. observed increased penile length in response to dihydrotestosterone gel in a 13-y-old child who was clearly in pubertal development, we observed almost similar magnitude of response in our patient at the age of one year. We opine that if treatment is initiated at a young age, it may help in lessening parental anxiety… 

References

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5 α-Reductase Type 2 Deficiency: Response to Dihydrotestosterone Gel
TLDR
A child with 46 XY Disorder of Sexual Differentiation (DSD), due to 5α-reductase deficiency, who was managed with Dihydrotestosterone (DHT) gel is described.
Gender Change in 46,XY Persons with 5α-Reductase-2 Deficiency and 17β-Hydroxysteroid Dehydrogenase-3 Deficiency
Individuals with 5α-reductase-2 deficiency (5α-RD-2) and 17β-hydroxysteroid dehydrogenase-3 deficiency (17β-HSD-3) are often raised as girls. Over the past number of years, this policy has been
Gender Identity of Children and Young Adults with 5α-Reductase Deficiency
TLDR
It is concluded that all patients with this disorder had male gender identity from early childhood, and the parents took note of this only after the appearance of male secondary sexual characteristics at puberty, thereby giving an impression of change in gender identity and gender role.
Gender identity of children and young adults with 5alpha-reductase deficiency.
TLDR
It is concluded that all patients with this disorder had male gender identity from early childhood, and the parents took note of this only after the appearance of male secondary sexual characteristics at puberty, thereby giving an impression of change in gender identity and gender role.