5′ end of hmg CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcription

@article{Osborne19855EO,
  title={5′ end of hmg CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcription},
  author={Timothy F. Osborne and Joseph L. Goldstein and Michael S. Brown},
  journal={Cell},
  year={1985},
  volume={42},
  pages={203-212}
}
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Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme
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TLDR
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