5‐hydroxymethylfurfural‐ and fluorescein‐fused fluorescence probe of mast cells (RBL‐2H3): Synthesis, photophysical properties, and bioimaging

@article{Huang20185hydroxymethylfurfuralAF,
  title={5‐hydroxymethylfurfural‐ and fluorescein‐fused fluorescence probe of mast cells (RBL‐2H3): Synthesis, photophysical properties, and bioimaging},
  author={Limin Huang and Di Wei and Zibo Wu and Yajing Hou and Yitong Xie and Zhenru Liu and Cheng Wang and Delu Che and Yibo Lei and Huaizhen He},
  journal={Chemical Biology \& Drug Design},
  year={2018},
  volume={92},
  pages={1963 - 1971}
}
A fluorescent probe (Fluo‐HMF) was developed via introduction of a furfural moiety into the fluorescein molecular skeleton, aiming at specially labeling cell membrane of mast cells. To illustrate its specificity, we designed and synthesized a series of fluorescent compounds based on fluorescein molecular skeleton. The fluorescent properties of Fluo‐HMF were investigated, which were in accordance with theoretical calculations. Compared with other fluorescein derivatives, Fluo‐HMF could specially… Expand
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