5' upstream sequence and genomic structure of the human primary response gene, EGR-1/TIS8.

@article{Sakamoto19915US,
  title={5' upstream sequence and genomic structure of the human primary response gene, EGR-1/TIS8.},
  author={Kathleen M Sakamoto and Carolyne Bardeleben and Kristin E. Yates and Mark Raines and David W. Golde and Judith C. Gasson},
  journal={Oncogene},
  year={1991},
  volume={6 5},
  pages={867-71}
}
EGR-1/TIS8 is a primary response gene that encodes a zinc finger containing protein and is induced in a number of cell types by a variety of ligands. We have isolated and mapped the human EGR-1/TIS8 gene and sequenced the 5' upstream flanking region. A 'TATA' homology and several putative regulatory elements, including two Sp1 sites, five serum response-like elements, two cAMP response-like elements, an EGR-1 binding site (EBS), and a tetra-decanoyl phorbol acetate (TPA)-responsive element have… CONTINUE READING

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