5' and 3' untranslated regions of pestivirus genome: primary and secondary structure analyses.

@article{Deng19935A3,
  title={5' and 3' untranslated regions of pestivirus genome: primary and secondary structure analyses.},
  author={R L Deng and Kenneth V Brock},
  journal={Nucleic acids research},
  year={1993},
  volume={21 8},
  pages={1949-57}
}
Within the conserved 5' untranslated region (UTR) of the pestivirus genome three highly variable regions were identified. Preceding the polyprotein start codon, multiple cryptic AUG codons and several small open reading frames are characteristic for all the five pestiviruses. Inspection of the context of AUGs revealed that the polyprotein initiation AUG of pestivirus has a weak context for efficient translation initiation. The most favorable context was found in two of the cryptic AUGs. Two… CONTINUE READING